How much storage do you need? If it’s just 2TB - or if you’re just future proofing it and don’t anticipate needing more than 2TB within the next few years - I’d pick one SSD. Even the cheaper ones will give you a better performance than an SSD + HDD combo.
I use it on Cyberpunk without issues. But regardless of platform, it needs to be paired with DLSS or FSR to mitigate the huge performance hit. I think it will still take 5+ years for it to become the expected way to run a new photo-realistic game.