• 3 Posts
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Joined 2 years ago
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Cake day: June 16th, 2023

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  • I’d add on that the expectation in an individualist society like the US is to become independent and move out. Those ideas are used synonymously in a lot of contexts. Someone who hasn’t moved out can be seen as lacking independence. Of course that isn’t necessarily true, but it’s the perception.

    For a young person growing up with these ideas as the standard, there can be a certain safety in forgoing that independence. That was my situation for years, where I was financially independent, but moved back home after my roommates moved away. I was in my mid twenties before I moved out for good.






  • From the article, not in OP’s summary:

    In 2007, the FDA published guidance on regulatory limits for DNA vaccines in the Guidance for Industry: Considerations for Plasmid DNA Vaccines for Infectious Disease Indications (Guidance for Industry). In this Guidance for Industry, the FDA outlines important considerations for vaccines that use novel methods of delivery regarding DNA integration, specifically:

    • DNA integration could theoretically impact a human’s oncogenes – the genes which can transform a healthy cell into a cancerous cell.

    • DNA integration may result in chromosomal instability.

    • The Guidance for Industry discusses biodistribution of DNA vaccines and how such integration could affect unintended parts of the body including blood, heart, brain, liver, kidney, bone marrow, ovaries/testes, lung, draining lymph nodes, spleen, the site of administration and subcutis at injection site.

    On December 14, 2023, the FDA provided a written response providing no evidence that DNA integration assessments have been conducted to address risks outlined by the FDA themselves in 2007. Based on the FDA’s recognition of unique risks posed by DNA integration, the efficacy of the COVID-19 mRNA vaccine’s lipid nanoparticle delivery system, and the presence of DNA fragments in these vaccines, it is essential to human health to assess the risks of contaminant DNA integration into human DNA. The FDA has provided no evidence that these risks have been assessed to ensure safety. As such, Florida State Surgeon General Dr. Joseph A. Ladapo has released the following statement:

    “The FDA’s response does not provide data or evidence that the DNA integration assessments they recommended themselves have been performed. Instead, they pointed to genotoxicity studies – which are inadequate assessments for DNA integration risk. In addition, they obfuscated the difference between the SV40 promoter/enhancer and SV40 proteins, two elements that are distinct.

    DNA integration poses a unique and elevated risk to human health and to the integrity of the human genome, including the risk that DNA integrated into sperm or egg gametes could be passed onto offspring of mRNA COVID-19 vaccine recipients. If the risks of DNA integration have not been assessed for mRNA COVID-19 vaccines, these vaccines are not appropriate for use in human beings.

    Providers concerned about patient health risks associated with COVID-19 should prioritize patient access to non-mRNA COVID-19 vaccines and treatment. It is my hope that, in regard to COVID-19, the FDA will one day seriously consider its regulatory responsibility to protect human health, including the integrity of the human genome.”











  • Like others are saying, probably a clogged nozzle. However, I want to say I just went through this myself and it was not a clogged nozzle. At temperature, I could put light pressure on the filament with my hand and it would come out smoothly, no clog. It can also be that your nozzle is too close to the print bed. In my case, it would do this even when suspended in the air, so that was not the issue.

    I upgraded to a metal extruder, and no longer have this issue.

    Despite what most people say, sometimes parts are the problem. This other commenter explained better.